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曹先招 马 捷

030000 太原,山西医科大学(曹先招);山西医科大学第二医院心胸外科(马捷)


摘 要:主动脉瓣狭窄(AS)合并高血压在临床中较常见。AS合并高血压时可以额外增加AS患者左心室后负荷,导致左心室肥厚加重,临床 症状发生提前,心血管事件发生率及死亡率比单纯AS时明显增加,临床上需要引起特别重视。另外,高血压可以显著影响跨主动脉瓣口流速, 干扰AS临床分级,而AS临床分级是确定治疗方案的基础,因此,在评估AS狭窄程度时应尽量使血压控制在理想水平。AS合并高血压抗高血压药 物治疗时,潜在低血压导致的重要脏器灌注不足风险明显增加,且其有效性尚缺乏大量临床证据支持。本文从AS合并高血压血流动力学变化、 左心室面临的后负荷及继发影响、应对策略作一综述。

关键词:主动脉瓣狭窄; 高血压; 瓣膜-血管阻力; 治疗

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文献标引:曹先招 马 捷.高血压对主动脉瓣狭窄诊疗的影响及应对策略[J/CD].心血管外科杂志:电子版,2016,5(2):24.

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