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心脏术后心力衰竭的药物治疗作用机制

逯若逸 宋元申 韩宏光

121000 辽宁锦州,锦州医科大学研究生院15级(逯若逸、宋元申);沈阳军区总医院心外科(韩宏光)

韩宏光,Email: hanxiyao@163.com

摘 要:心力衰竭(HF)是由于心脏泵功能出现异常而发生的严重临床症状,通常表现为肺水肿引起的呼吸困难、单心室或双心室的充血性 HF、心源性休克。心脏术后急性HF患者心功能差,预后不佳,因此合理的用药和精心的处理尤为重要。正性肌力药物可避免多脏器功能衰竭的 发生。正性肌力药可单一也可以联合使用,但目前尚缺乏在心脏术后HF中应用的专家共识与随机对照试验。随着β受体阻滞剂和盐皮质激素受 体拮抗剂(MRA)、血管紧张素受体阻滞剂(ARB)、血管紧张素转移酶抑制剂(ACEI)等药物的出现,心脏术后合并HF的药物治疗取得了重要 进展。本文就新研发的抗HF药物作用机制及其研究进展作一综述。

关键词:心脏外科手术; 心力衰竭; 药物疗法; 作用机制

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文献标引:逯若逸 宋元申 韩宏光.心脏术后心力衰竭的药物治疗作用机制[J/CD].心血管外科杂志:电子版,2016,5(2):33.

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